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  • Title: Possible augmentation of antidepressant response by buspirone.
    Author: Jacobsen FM.
    Journal: J Clin Psychiatry; 1991 May; 52(5):217-20. PubMed ID: 2033029.
    Abstract:
    In open trials, seven of eight antidepressant nonresponders reported partial or full antidepressant response after the addition of buspirone 10 mg t.i.d. An additional eight of nine patients who suffered winter relapses of depression while receiving previously effective antidepressant regimens showed remission of depressive symptoms after the addition of buspirone 10 mg t.i.d. Improvement after the addition of buspirone was maintained for at least 3 months, and side effects were minimal in most patients. These results suggest that low doses of buspirone may be useful in augmenting antidepressant response.
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