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  • Title: Valve-sparing operation for aortic root aneurysm in patients with Marfan syndrome.
    Author: Wang R, Ma WG, Tian LX, Sun LZ, Chang Q.
    Journal: Thorac Cardiovasc Surg; 2010 Mar; 58(2):76-80. PubMed ID: 20333568.
    Abstract:
    BACKGROUND: We report our experience with aortic valve-sparing procedures in patients with Marfan syndrome and aortic root aneurysm. METHODS: Between August 2003 and July 2007, we performed aortic valve-sparing procedures in 20 patients with aortic root aneurysm resulting from Marfan syndrome. Mean age was 28 +/- 10 years (range, 10 to 57 years), and there were 9 females and 11 males. A reimplantation technique was used in 9 cases, a remodeling technique in 8 and a patch technique in 3 cases. Additional procedures included total aorta replacement in 1 patient, and aortic arch replacement plus stented elephant trunk in 2 patients. The mean follow-up time was 46 +/- 16 months (range, 17 to 64 months). RESULTS: No in-hospital or late death occurred. Reexploration for bleeding was required in one case on postoperative day 1. No valve-related complications occurred during the follow-up period. At the end of follow-up, trivial or no aortic regurgitation was demonstrated in 14 patients, mild in 4 patients, moderate in 1 and severe in 1. Two patients with moderate and severe aortic regurgitation required reoperation. CONCLUSIONS: The early and mid-term results of the valve-sparing operations were favorable, and the durability of the preserved valve should encourage use of this technique in patients with Marfan syndrome.
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