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  • Title: Late preterm birth and risk of developing asthma.
    Author: Abe K, Shapiro-Mendoza CK, Hall LR, Satten GA.
    Journal: J Pediatr; 2010 Jul; 157(1):74-8. PubMed ID: 20338577.
    Abstract:
    OBJECTIVE: To evaluate the association between gestational age at birth (late preterm vs term) and risk for physician-diagnosed asthma. STUDY DESIGN: We conducted a retrospective cohort study using the Third National Health and Nutrition Examination Survey (1988-1994) linked natality files. The study included children age 2-83 months from singleton births, born late preterm (n=537) or term (n=5650). Using survival analysis, we modeled time to diagnosis of asthma; children with no asthma diagnosis were censored at the age of their survey interview. We used Cox proportional hazard regression to estimate hazard ratios and 95% confidence intervals for gestational age and asthma risk, adjusting for maternal age, maternal education, parental history of asthma/hay fever, maternal smoking history during pregnancy, race/ethnicity, and sex of the child. RESULTS: Adjusted analysis showed that physician-diagnosed asthma was modestly associated with late preterm birth (hazard ratio, 1.3; 95% confidence interval, 0.8-2.0), but this association was not statistically significant (P=.30). CONCLUSIONS: Our study found that late preterm birth was not associated with a diagnosis of asthma in early childhood.
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