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  • Title: [A case of alveolar hemorrhage associated with mixed connective tissue disease].
    Author: Kobayashi O, Igarashi K, Sekiya M, Saito H.
    Journal: Nihon Kyobu Shikkan Gakkai Zasshi; 1991 Feb; 29(2):269-75. PubMed ID: 2033901.
    Abstract:
    A 52-year-old woman was admitted to our hospital because of anemia and abnormal lung shadow. She had Raynaud's symptom for 6 months, and recently developed cough and easy fatigability. She had thrombocytopenia, restrictive pulmonary dysfunction, and swollen fingers. ANF was positive (X1280), and anti-RNP antibody was also positive. Mixed connective tissue disease was diagnosed. Chest X-ray showed a diffuse alveolar pattern, and BAL revealed many hemosiderin-laden macrophages. Alveolar hemorrhage was suspected. The pulmonary shadow resolved spontaneously, and no recurrence occurred after steroid and immunosuppressant therapy.
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