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  • Title: [The immunogenicity of the hepatitis B vaccine in drug addicts with human immunodeficiency virus infection].
    Author: Menicagli V, Barbanera M, Menicagli S.
    Journal: Recenti Prog Med; 1991 Feb; 82(2):69-71. PubMed ID: 2034870.
    Abstract:
    In order to evaluate the antibody response to anti-hepatitis B vaccine, 21 heroin addicted with HIV infection previously vaccinated, were studied. 18 patients were asymptomatic and 3 were at the LAS stage. An antibody response was estimated at 1 and 12 months after the end of the vaccination. The first control showed that 62% presented a protective anti-HBs (higher than 10 mU/ml); after one year 70% of responders had a persistent immunity. The antibody response showed no correlation with the value of immunologic tests; the vaccine showed neither a significant evidence of side-effects nor a negative influence on the HIV infection.
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