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  • Title: A case of virus associated hemophagocytic syndrome and malignant histiocytosis: sometimes a difficult distinction.
    Author: Vespignani S, Sardeo G, Castronovo S, Galassi A, Venza E.
    Journal: Recenti Prog Med; 1991 Feb; 82(2):80-2. PubMed ID: 2034873.
    Abstract:
    The differential diagnosis among hemophagocytic syndromes and particularly between the virus-associated hemophagocytic syndrome (VAHS) and the malignant histiocytosis (HM) is quite easy in typical cases. Difficulties of interpretation may sometimes ensue when viral-bacteriologic work-ups indicative of VAHS are negative and/or morphologic histiocytic aberrations indicative of HM are missing. The authors present a case of hemophagocytic syndrome with the latter characteristics and discuss the differential diagnosis.
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