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  • Title: Histochemical localization of opiate receptors and opioid peptides.
    Author: Kuhar MJ.
    Journal: Fed Proc; 1978 Feb; 37(2):153-7. PubMed ID: 203493.
    Abstract:
    It is possible to localize opiate receptors by histochemical methods. They appear in high densities in anatomical areas associated with physiologic functions altered by opiates. They appear to mediate inhibitory responses; some of them, in certain regions could be involved in axo-axonic synapses. The immunohistochemical studies as well as the electrophysiologic results are compatible with the view that the enkephalins are the endogenous substrates for the opiate receptors.
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