These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Unusual photophysical properties of a ruthenium(II) complex related to [Ru(bpy)2(dppz)]2+.
    Author: Sun Y, Collins SN, Joyce LE, Turro C.
    Journal: Inorg Chem; 2010 May 03; 49(9):4257-62. PubMed ID: 20353166.
    Abstract:
    A new ruthenium polypyridyl complex, [Ru(bpy)(2)(dpqp)](2+) (bpy = 2,2'-bipyridne; dpqp = pyrazino[2',3':5,6]pyrazino[2,3-f][1,10]phenanthroline), shows strong luminescence in water at room temperature, a behavior that is strikingly different from that of the nonemissive "DNA light-switch" prototype [Ru(bpy)(2)(dppz)](2+) (dppz = dipyrido[3,2-a:2'-3'-c]phenazine) under similar conditions. Variation of the absorption and emission spectra of [Ru(bpy)(2)(dpqp)](2+) as a function of the pH is consistent with the occurrence of two ground-state protonation steps associated with the dpqp ligand and an apparent pK(a)* of 2.1. Electrochemistry and theoretical calculations indicate that the lowest unoccupied molecular orbital (LUMO) of [Ru(bpy)(2)(dpqp)](2+) is localized on the distal portion of the dpqp ligand and lies at a lower energy than the dppz-based LUMO of [Ru(bpy)(2)(dppz)](2+). The combination of its strong DNA binding affinity and relatively long-lived triplet metal-to-ligand charge-transfer excited state in an aqueous solution results in more efficient DNA photocleavage by [Ru(bpy)(2)(dpqp)](2+) than [Ru(bpy)(2)(dppz)](2+).
    [Abstract] [Full Text] [Related] [New Search]