These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Regulation and role of organic anion-transporting polypeptides (OATPs) in drug delivery at the choroid plexus.
    Author: Zhang H, Song YN, Liu WG, Guo XL, Yu LG.
    Journal: J Clin Neurosci; 2010 Jun; 17(6):679-84. PubMed ID: 20356750.
    Abstract:
    The organic anion-transporting polypeptides (rodents: Oatps; human: OATPs) belong to the growing family of organic anion/prostaglandin transporters and are important components of the active efflux transport system at the choroid plexus epithelial cells. OATPs facilitate the elimination of xenobiotics and endogenous waste from the cerebrospinal fluid and prevent waste accumulation in the central nervous system (CNS). This review summarizes the structures, regulations and roles of Oatps/OATPs at the choroid plexus in drug delivery to the CNS.
    [Abstract] [Full Text] [Related] [New Search]