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  • Title: Label-free and naked eye detection of PNA/DNA hybridization using enhancement of gold nanoparticles.
    Author: Kim SK, Cho H, Jeong J, Kwon JN, Jung Y, Chung BH.
    Journal: Chem Commun (Camb); 2010 May 21; 46(19):3315-7. PubMed ID: 20361103.
    Abstract:
    Utilizing a gold enhancement process after inducing electrostatic interaction between positively charged gold nanoparticles and negatively charged target DNA hybridized to neutral PNA capture probes, a new method for label-free detection of DNA was developed and successfully applied to detect H5-type DNA.
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