These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Some characteristics of sodium-independent phosphate transport across renal basolateral membranes.
    Author: Azzarolo AM, Ritchie G, Quamme GA.
    Journal: Biochim Biophys Acta; 1991 May 07; 1064(2):229-34. PubMed ID: 2036438.
    Abstract:
    Sodium-independent phosphate transport was evaluated in porcine renal basolateral membrane vesicles. Phosphate uptake was saturable with an apparent Km 10.1 +/- 1.2 mM and Vmax 13.6 +/- 2.0 nmol (mg protein)-1 min-1, n = 5. Phosphate uptake was trans-stimulated with intravesicle phosphate and was enhanced with a positive transmembrane electrical potential. Arsenate and bicarbonate inhibited phosphate transport but other anions including sulfate and phosphonoformate were without effect. These studies indicate that phosphate uptake across basolateral membranes is present in the absence of sodium, is facilitated, and is specific for phosphate. The apparent affinity and rate of phosphate transport across the basolateral membrane is significantly higher than the respective parameters observed for the brush-border membrane.
    [Abstract] [Full Text] [Related] [New Search]