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Title: Elastic energy of protein-DNA chimeras. Author: Tseng CY, Wang A, Zocchi G, Rolih B, Levine AJ. Journal: Phys Rev E Stat Nonlin Soft Matter Phys; 2009 Dec; 80(6 Pt 1):061912. PubMed ID: 20365195. Abstract: We present experimental measurements of the equilibrium elastic energy of protein-DNA chimeras, for two different sets of attachment points of the DNA "molecular spring" on the surface of the protein. Combining these with measurements of the enzyme's activity under stress and a mechanical model of the system, we determine how the elastic energy is partitioned between the DNA and the protein. The analysis shows that the protein is mechanically stiffer than the DNA spring.[Abstract] [Full Text] [Related] [New Search]