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  • Title: Anaesthetic-induced ventricular tachyarrhythmia in Jervell and Lange-Nielsen syndrome.
    Author: Adu-Gyamfi Y, Said A, Chowdhary UM, Abomelha A, Sanyal SK.
    Journal: Can J Anaesth; 1991 Apr; 38(3):345-6. PubMed ID: 2036697.
    Abstract:
    A four-year-old deaf girl with a history of convulsions developed polymorphous ventricular tachycardia during induction of anaesthesia. The arrhythmia reverted to sinus rhythm spontaneously. Post-anaesthetic ECG showed marked prolongation of the QTc interval (570-690 msec). Deafness and prolonged QTc interval in association with microcytic-hypochromic anaemia confirmed the diagnosis of the Jervell and Lange-Nielsen syndrome. This case report highlights the potentially lethal complication of halothane anaesthesia in patients with long QTc interval syndrome.
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