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  • Title: [Varicocele and male infertility].
    Author: Huang YF.
    Journal: Zhonghua Nan Ke Xue; 2010 Mar; 16(3):195-200. PubMed ID: 20369544.
    Abstract:
    Varicocele is a most common and surgically correctable cause of male infertility, for which varicocelectomy is the major treatment. Recent years have witnessed a lot of efforts devoted to the pathomechanism of varicocele-induced male infertility and rapid progress in researches on its cellular and molecular mechanisms, mainly including apoptotic abnormality and oxidative stress of germ cells. Meanwhile, researchers are coming to a consensus on the indications of varicocelectomy as well as the advantages and disadvantage of different methods of the procedure. This review updates the cellular and molecular mechanisms of varicocele-induced male infertility and its clinical therapeutic strategies.
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