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  • Title: Cytotoxic activity of epsilon-aminocaproylamino acids in breast cancer MCF-7 and fibroblast cell lines.
    Author: Midura-Nowaczek K, Markowska A, Krajewska D, Wołczyński S.
    Journal: Acta Pol Pharm; 2010; 67(2):201-4. PubMed ID: 20369798.
    Abstract:
    The effect of H-EACA-L-Cys(S-Bzl)-OH, H-EACA-L-Leu-OH, H-EACA-L-Nle-OH and EACA on the viability of MCF-7 and fibroblast cells was examined. The antibacterial activity of these compounds was also tested. H-EACA-L-Leu-OH and H-EACA-L-Nle-OH showed cytotoxic activity against MCF-7 and fibroblast cell lines, particularly in the highest studied 20 mM concentration. None of the examined dipeptides showed antibacterial activity.
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