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  • Title: Type B insulin resistance in a systemic lupus erythematosus patient.
    Author: Ostwal V, Oak J.
    Journal: Int J Rheum Dis; 2009 Jul; 12(2):174-6. PubMed ID: 20374339.
    Abstract:
    In type B insulin resistance and acanthosis nigricans, the insulin resistance is due to the presence of anti-insulin receptor antibody 1. Approximately one-third of patients with these antibodies have an associated illness such as systemic lupus erythematosus (SLE) or Sjögren's syndrome. This report describes a case wherein the patient had presented with uncontrolled diabetes and required > 3000 units of human insulin to control hyperglycemia. She also had features of SLE. There was complete recovery following treatment with steroids.
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