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  • Title: Determination of beta-agonists in pig feed, pig urine and pig liver using capillary electrophoresis with electrochemical detection.
    Author: Wang W, Zhang Y, Wang J, Shi X, Ye J.
    Journal: Meat Sci; 2010 Jun; 85(2):302-5. PubMed ID: 20374903.
    Abstract:
    The fast separation capability of a capillary electrophoresis with electrochemical detection (CE-ED) system was demonstrated by determining five beta-agonists including clenbuterol, metoprolol, ractopamine, isoxsuprine and salbutamol in several real samples. Factors influencing the separation and detection were examined and optimized. Under the optimum conditions, the five beta-agonists could be well separated within 15min at a separation voltage of 14kV in a 100mmoL H(3)BO(3)-Na(2)B(4)O(7) running buffer (pH 9.0). This method was successfully used in the analysis of clenbuterol, metoprolol, ractopamine, isoxsuprine and salbutamol in pig feed, pig urine and pig liver, providing a useful method for monitoring the illegal use of beta-agonists from growth promotion in food-producing animals.
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