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  • Title: DDT contamination from indoor residual spraying for malaria control.
    Author: Van Dyk JC, Bouwman H, Barnhoorn IE, Bornman MS.
    Journal: Sci Total Environ; 2010 Jun 01; 408(13):2745-52. PubMed ID: 20381127.
    Abstract:
    The insecticide DDT is still used in specific areas of South Africa for indoor residual spray (IRS) to control malaria vectors. Local residents could be exposed to residues of DDT through various pathways including indoor air, dust, soil, food and water. The aims of this study were to determine the levels of DDT contamination, as a result of IRS, in representative homesteads, and to evaluate the possible routes of human exposure. Two villages, exposed (DV) and reference (TV) were selected. Sampling was done two months after the IRS process was completed. Twelve homesteads were selected in DV and nine in TV. Human serum, indoor air, floor dust, outside soil, potable water, leafy vegetables, and chicken samples (muscle, fat and liver) were collected and analyzed for both the o,p'- and p,p'-isomers of DDT, DDD and DDE. DDT was detected in all the media analyzed indicating a combination of potential dietary and non-dietary pathways of uptake. DV had the most samples with detectable levels of DDT and its metabolites, and with the exception of chicken muscle samples, DV also had higher mean levels for all the components analyzed compared to TV. Seventy-nine percent of participants from DV had serum levels of DDT (mean [summation operator]DDT 7.3microg g(-1) lipid). These residues constituted mainly of p,p'-DDD and p,p'-DDE. [summation operator]DDT levels were detected in all indoor air (mean [summation operator]DDT 3900.0 ng m(-3)) and floor dust (mean [summation operator]DDT 1200.0 microg m(-2)) samples. Levels were also detected in outside soil (mean [summation operator]DDT 25.0 microg kg(-1)) and potable water (mean [summation operator]DDT 2.0 microg L(-1)). Vegetable sample composition (mean [summation operator]DDT 43.0 microg kg(-1)) constituted mainly p,p'-DDT and p,p'-DDD. Chicken samples were highly contaminated with DDT (muscle mean [summation operator]DDT 700.0 microg kg(-1), fat mean [summation operator]DDT 240,000.0 microg kg(-1), liver mean [summation operator]DDT 1600.0 microg kg(-1)). The results of the current study raise concerns regarding the potential health effects in residents living in the immediate environment following DDT IRS.
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