These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Association of electrocardiographic changes with severity of coronary artery disease and short term outcome in patients with non-ST-segment elevation acute coronary syndromes.
    Author: Ghaffari S, Separham A, Pourafkari L.
    Journal: Saudi Med J; 2010 Apr; 31(4):400-5. PubMed ID: 20383417.
    Abstract:
    OBJECTIVE: To assess the association between electrocardiogram (ECG) changes in non-ST-segment elevation acute coronary syndrome (NSTE- ACS) patients with severity of coronary artery disease (CAD) and short-term outcome. METHODS: In this cross-sectional descriptive-analytical study, 111 patients admitted to the Cardiology Department of Shahid Madani Heart Hospital, Tabriz, Iran between March 2005 and March 2007 with first NSTE-ACS, and had undergone coronary angiography during index event were evaluated. RESULTS: One hundred and eleven patients (64 males, and 47 females) were enrolled, and their in-hospital and short-term outcome with a mean follow-up period of 4.6 +/- 1.8 months was evaluated. Patients with ST-T changes on admission had higher rates of death (16.7 versus 2.7%, p=0.01), recurrent angina (36.1 versus 6.7%, p=0.001), and pulmonary edema (8.3 versus 1.3%, p=0.045). The mean left ventricular ejection fraction (LVEF) of patients with ECG changes were significantly lower than those without ECG changes (p=0.001). Mitral regurgitation (MR) was also more common among those with ECG changes (p=0.006). In a multivariate regression analysis, the only independent predictor of short-term mortality and adverse clinical event was ST depression on ECG (p=0.001). CONCLUSION: In patients with first NSTE-ACS, ST deviation is associated with adverse short-term outcome including more severe CAD, lower LVEF, and more common MR.
    [Abstract] [Full Text] [Related] [New Search]