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Title: Apoptosis: conserved roles for integrins in clearance. Author: D'mello V, Birge RB. Journal: Curr Biol; 2010 Apr 13; 20(7):R324-7. PubMed ID: 20392425. Abstract: A recent study shows that one of the two known Caenorhabditis elegans homologs of the mammalian integrin alpha subunit plays an essential role in the clearance of apoptotic cells - efferocytosis - during nematode development. These new findings reveal that integrins have evolutionarily conserved functions in efferocytosis in metazoans.[Abstract] [Full Text] [Related] [New Search]