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  • Title: Ultrahigh resolution optical coherence tomography with femtosecond Ti:sapphire laser and photonic crystal fiber.
    Author: Ping X, Fujimoto JG.
    Journal: Chin Sci Bull; 2008 Jul 01; 53(13):1963-1966. PubMed ID: 20396625.
    Abstract:
    Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-continuum generated by coupling femtosecond pulses from a commercial Ti:sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 μm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample, only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated, showing great potential for biomedical application.
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