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  • Title: Non-enzymatic amperometric glucose biosensor based on nickel hexacyanoferrate nanoparticle film modified electrodes.
    Author: Wang X, Zhang Y, Banks CE, Chen Q, Ji X.
    Journal: Colloids Surf B Biointerfaces; 2010 Jul 01; 78(2):363-6. PubMed ID: 20409695.
    Abstract:
    A non-enzymatic amperometric glucose biosensor based on the modification of functional nickel hexacyanoferrate nanoparticles was prepared via electrochemical deposition. The electrochemical deposition of the nickel hexacyanoferrate nanoparticles was obtained by potential cycling in a solution containing nickel (II) and hexacyanoferrate (III) producing a modified surface with a high degree of uniformity. The modified electrode is exemplified towards the non-enzymatic sensing of glucose where using cyclic voltammetry and amperometry, low micro-molar up to milli-molar glucose concentrations are readily detectable. The non-enzymatic sensing of glucose also shows a modest selectivity over ascorbic acid. This platform offers a novel route for glucose sensors with wide analytical applications.
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