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  • Title: Chemical components from the Vietnamese soft coral Lobophytum sp.
    Author: Nguyen HT, Chau VM, Phan VK, Hoang TH, Nguyen HN, Nguyen XC, Tran HQ, Nguyen XN, Hyun JH, Kang HK, Kim YH.
    Journal: Arch Pharm Res; 2010 Apr; 33(4):503-8. PubMed ID: 20422357.
    Abstract:
    Chromatographic separation resulted in the identification of one new squalene derivative, named lobophytene (1), three cembranoid diterpenes (2-4), and two sterols (5 and 6) from the Vietnamese marine soft coral Lobophytum sp. Their structures were identified on the basis of extensive spectroscopic data and comparison of those with reported data. Compounds 1 and 2 showed significant cytotoxic activities against lung (A549) and colon (HT-29) cell lines with IC(50) values of 8.2 and 5.6 microM for 1; 5.1 and 1.8 microM for 2, respectively.
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