These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Study of components in xingnaojing affecting intestine absorption of gardenia extract].
    Author: Du S, Zhang Q, Lu Y, Zhai Y, Wu Q.
    Journal: Zhongguo Zhong Yao Za Zhi; 2010 Feb; 35(3):297-300. PubMed ID: 20422992.
    Abstract:
    OBJECTIVE: To observe the influence of ingredients in Xingnaojing,such as moschus, borneol and radix curcumae on intestine absorption kinetics of gardenia extract. METHOD: An in situ intestinal perfusion model of rats was employed to investigate the absorption of geniposide in gardenia extract. RESULT: While gardenia extract was administered solely, the absorptive rate constant (K) of geniposide was (0.055 +/- 0.006) h(-1); But while the extract was co-administered with radix curcumae,moschus and borneol, the K were (0.060 +/- 0.001), (0.066 +/- 0.008), (0.072 +/- 0.010) h(-1), respectively. The K was (0.076 +/- 0.011) h(-1) while the extract in total formulation for Xingnaojing. CONCLUSION: The K, while the extract is co-administered with borneol or total formulation is significantly higher than solely used. Borneol and complex prescription can significantly increase the intestinal absorption of geniposide in gardenia extract.
    [Abstract] [Full Text] [Related] [New Search]