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  • Title: MR to ultrasound image registration for guiding prostate biopsy and interventions.
    Author: Hu Y, Ahmed HU, Allen C, Pendsé D, Sahu M, Emberton M, Hawkes D, Barratt D.
    Journal: Med Image Comput Comput Assist Interv; 2009; 12(Pt 1):787-94. PubMed ID: 20426060.
    Abstract:
    A method is described for registering preoperative magnetic resonance (MR) to intraoperative transrectal ultrasound (TRUS) images of the prostate gland. A statistical motion model (SMM) of the prostate is first built using training data provided by biomechanical simulations of the motion of a patient-specific finite element model, derived from a preoperative MR image. The SMM is then registered to a 3D TRUS image by maximising the likelihood of the shape of an SMM instance given a voxel-intensity-based feature, which represents an estimate of normal vector at the surface of the prostate gland. Using data acquired from 7 patients, the accuracy of registering T2 MR to 3D TRUS images was evaluated using anatomical landmarks inside the gland. The results show that the proposed registration method has a root-mean-square target registration error of 2.66 mm.
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