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  • Title: Serum proteinogram of cats experimentally infected by Trypanosoma evansi.
    Author: Costa MM, da Silva AS, Wolkmer P, Zanette RA, França RT, Monteiro SG, dos Anjos Lopes ST.
    Journal: Prev Vet Med; 2010 Jul 01; 95(3-4):301-4. PubMed ID: 20444513.
    Abstract:
    This study was aimed at evaluating the electrophoretic profile of serum proteins in Trypanosoma evansi-infected cats during different periods of infection. Thirteen adult females non-breeding Felis catus were separated into two groups. Animals from the infected group (n=7) were inoculated intraperitoneally with a strain of T. evansi; whereas, animals from the control group (n=6) received a physiological solution. Blood samples were collected at days 0, 7, 21, and 35 for total protein evaluation and protein fractionation by electrophoresis. Albumin (P<0.01), alpha-2 globulin and gamma globulin (P<0.05) concentrations were statistically different from the seventh day post-inoculation onwards. Beta-globulin levels were increased from day 21 onwards (P<0.05). Alpha-1 globulin fraction did not differ statistically. These results indicate that the infection by T. evansi in cats alters the serum protein electrophoretic profile.
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