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  • Title: Disseminated Mycobacterium avium complex infection in a non-HIV-infected patient undergoing continuous ambulatory peritoneal dialysis.
    Author: Chung JW, Cha YJ, Oh DJ, Nam WJ, Kim SH, Lee MK, Kim HR.
    Journal: Korean J Lab Med; 2010 Apr; 30(2):166-70. PubMed ID: 20445335.
    Abstract:
    Isolated bone marrow infection by nontuberculous mycobacteria (NTM) is extremely rare. Recently, we encountered a case of bone marrow Mycobacterium avium complex (MAC) infection, which presented as a fever of unknown origin shortly after starting continuous ambulatory peritoneal dialysis (CAPD). The patient was diagnosed with MAC infection on the basis of PCR-restriction fragment length polymorphism analysis and sequencing of DNA obtained from bone marrow specimens. Although this was a case of severe MAC infection, there was no evidence of infection of other organs. End-stage renal disease (ESRD) patients undergoing dialysis can be considered immunodeficient; therefore, when these patients present with fever of unknown origin, opportunistic infections such as NTM infection should be considered in the differential diagnosis.
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