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  • Title: Octreotide reduces hepatic, renal and breast cystic volume in autosomal-dominant polycystic kidney disease.
    Author: Peces R, Cuesta-López E, Peces C, Pérez-Dueñas V, Vega-Cabrera C, Selgas R.
    Journal: Int Urol Nephrol; 2011 Jun; 43(2):565-9. PubMed ID: 20449653.
    Abstract:
    A 43-year-old woman with autosomal-dominant polycystic kidney disease (ADPKD) received octreotide for 12 months, and this was associated with a 6.3% reduction in liver volume, an 8% reduction in total kidney volume and stabilization of renal function. There was also a reduction of cyst size in fibrocystic disease of breast. These data suggest that the cyst fluid accumulation in different organs from patients with ADPKD is a dynamic process which can be reversed by octreotide. This is the first report of a case of simultaneous reduction in hepatic, renal and breast cystic volume with preservation of renal function in a patient with ADPKD receiving octreotide.
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