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  • Title: Effects of ageing on postreceptoral short-wavelength gain control: transient tritanopia increases with age.
    Author: Werner A, Bayer A, Schwarz G, Zrenner E, Paulus W.
    Journal: Vision Res; 2010 Aug 06; 50(17):1641-8. PubMed ID: 20457174.
    Abstract:
    We investigated the effect of ageing on the neural gain control in the short-wavelength opponent channel. In order to tackle specifically postreceptoral changes, we determined the effect of ageing on transient tritanopia, a paradoxical and transient reduction of short-wavelength sensitivity after the presentation of a long-wavelength adapting light. The results demonstrate an unexpected and significant increase of transient tritanopia with age, which cannot be explained by a general decline of short-wave sensitivity or the selective reduction of retinal illumination. Instead, our data imply that ageing affects also short-wavelength gain control at the site of chromatic opponency or beyond. Age-related changes of adaptation processes should therefore be considered an important factor influencing the visual performances of the elderly.
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