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  • Title: [Comparative evaluation of the effects of ethacizine and Bonnecor in the treatment of supraventricular paroxysmal tachycardia].
    Author: Lukoshiavichiute AI, Gedrimene DA, Fol'kman G.
    Journal: Kardiologiia; 1991 Jan; 31(1):67-70. PubMed ID: 2046254.
    Abstract:
    The efficacy of ethacizine was investigated in 46 patients, whereas that of Bonnecor++ was examined in 31 patients who suffered from frequent episodes of supraventricular paroxysmal tachycardia. After intravenous administration of ethacizine and ++Bonnecor, tachycardia was sustained in 41 (89.1%) and 14 (45.0%) cases, respectively. Their arresting effect was observed in all 17 (100%) cases of nodal tachycardia and in 19 (82.6%) cases of orthodromic tachycardia. Moreover, the effect was obtained in 3 (75.0%) cases of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Bonnecor abolished an episode of nodal tachycardia only in 3 (23.0%) patients and that of orthodromic tachycardia in 9 (56.3%). Its effect was also seen in one case of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Anti-recurrence++ effects of ethacizine and ++Bonnecor in repeated episode provocation were seen in 26 (70.5%) and 10 (32.0%) cases, respectively. Side effects occurred more frequently when ethacizine was used.
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