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  • Title: Perioperative seizures following deep brain stimulation in patients with multiple sclerosis.
    Author: Johnson RD, Qadri SR, Joint C, Moir L, Green AL, Aziz TZ.
    Journal: Br J Neurosurg; 2010 Jun; 24(3):289-90. PubMed ID: 20465458.
    Abstract:
    Following a total of 386 deep brain stimulation (DBS) procedures in Oxford, only two seizures have been recorded in the peri-operative period. Both patients had MS and underwent thalamic DBS for tremor and these 2 cases are presented here. The incidence of peri-operative seizures in MS patients undergoing DBS procedures is more than 8-fold greater than that expected for patients undergoing DBS procedures. Further experience with DBS procedures in MS patients is needed to determine whether there is a role for peri-operative anticonvulsants in these patients.
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