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  • Title: Late solitary testicular metastasis from rectal cancer.
    Author: Venkitaraman R, George M, Weerasooriya S, Selva-Nayagam S.
    Journal: J Cancer Res Ther; 2010; 6(1):89-91. PubMed ID: 20479555.
    Abstract:
    Isolated testicular metastasis from rectal cancer is rare. We describe the case of a patient who presented with a locally advanced rectal malignancy and underwent multimodality treatment with low anterior resection, postoperative radiotherapy and adjuvant chemotherapy. He developed a painless testicular nodule while on follow-up, five years after the diagnosis of primary rectal cancer. Histopathology and immunohistochemistry of orchidectomy specimen were compatible with a metastatic adenocarcinoma of rectal origin. We hypothesize that this phenomenon of isolated relapse in a sanctuary site could be due to the altered biology and pattern of metastasis as a result of effective adjuvant systemic chemotherapy. Treatment of late isolated relapse in the testis needs to be ascertained.
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