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  • Title: [Chronic occupational bronchitis in workers of coal extracting enterprises in Kouzbass: role of endogenous factors].
    Author: Gafarov NI, Zakharenkov VV, Panev NI, Burdeĭn AV, Puzyrev VP, Rudko AA.
    Journal: Med Tr Prom Ekol; 2010; (3):37-40. PubMed ID: 20480820.
    Abstract:
    The authors studied distribution of biochemical markers for HP, GC, EsD, AcP genes, polymorphism of GSTT1 (GST-theta 1), GSTM1 (GST-mu 1), locus WNTR of NOS3 gene (alleles A/B) in chronic dust bronchitis patients and in apparently healthy individuals. Genotypes EsD 1-2 and AcP bb individuals were proved to be most prone to the disease. Endogenous resistent factors for chronic dust bronchitis are genotypes GC 1-1, EsD 1-1, AcP bc.
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