These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cytotoxic C(35) terpenoid cryptotrione from the bark of Cryptomeria japonica.
    Author: Chen CC, Wu JH, Yang NS, Chang JY, Kuo CC, Wang SY, Kuo YH.
    Journal: Org Lett; 2010 Jun 18; 12(12):2786-9. PubMed ID: 20481455.
    Abstract:
    A novel C(35)-terpene, designated as cryptotrione (1), with an unprecedented skeleton possessing an abietane diterpene with a unique bicyclic sesquiterpene, is identified from the bark of Cryptomeria japonica. The carbon skeleton of 1 represents a new structural entity, and this is an intriguing addition to the structurally diverse diterpene-sesquiterpene class. A unique biosynthetic pathway is proposed to support the production of this phytocompound. Notably, 1 exhibits anticancer activity with an IC(50) value of 6.44 +/- 2.23 microM.
    [Abstract] [Full Text] [Related] [New Search]