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  • Title: Synthesis and antimicrobial activities of two novel amino sugars derived from chloraloses.
    Author: Yenil N, Ay E, Ay K, Oskay M, Maddaluno J.
    Journal: Carbohydr Res; 2010 Jul 19; 345(11):1617-21. PubMed ID: 20488435.
    Abstract:
    The synthesis of 5-amino-5-deoxy-1,2-O-(S)-trichloroethylidene-beta-L-arabinofuranose and 6-amino-6-deoxy-1,2-O-(S)-trichloroethylidene-alpha-D-glucofuranose is described by a simple three- or four-step route. Antibacterial potency of the new compounds was determined using an inhibition zone diameter test. The results show that these compounds have a broad-spectrum activity against Gram-positive, Gram-negative bacteria and Candida albicans.
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