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  • Title: Accelerometer-determined steps/day and metabolic syndrome.
    Author: Sisson SB, Camhi SM, Church TS, Tudor-Locke C, Johnson WD, Katzmarzyk PT.
    Journal: Am J Prev Med; 2010 Jun; 38(6):575-82. PubMed ID: 20494233.
    Abstract:
    BACKGROUND: There is a lack of knowledge about the relationship between objectively measured physical activity and the odds of having metabolic syndrome (MetS) and cardiovascular (CVD) risk factors. PURPOSE: This study aims to investigate associations between accelerometer-determined steps/day and the odds of having MetS and its individual CVD risk factors in the U.S. population. METHODS: Adults in 2005-2006 NHANES with accelerometer-determined steps/day and measurements necessary to determine MetS by AHA/NHLBI were included (n=1446, 48.2% men, 33.5% with MetS, mean age=47.5 years, mean BMI=28.7 kg/m(2)). Logistic regression was used to estimate the odds of having MetS or abnormal CVD risk factors from incrementally higher levels of steps/day. RESULTS: MetS prevalence decreased as steps/day increased (p<0.0001), with 55.7% of participants in the lowest categoric level of steps/day and 13.3% in the highest level having MetS. The odds of having MetS were 10% lower for each additional 1000 steps/day (OR=0.90, 95% CI=0.86, 0.93). The likelihood of having MetS was OR=0.28 (95% CI=0.18, 0.44) for active to highly active and 0.60 (0.43, 0.82) for low to somewhat-active compared to sedentary adults (p<0.0001). Adults who took more steps/day tended to have lower waist circumference, higher high-density lipoprotein (HDL) cholesterol level, and lower levels of triglycerides. CONCLUSIONS: Adults who maintain an active lifestyle by accumulating more steps are likely to have a lower prevalence of MetS and its individual CVD risk factors. Although other concomitant lifestyle behaviors may influence this lower prevalence, the evidence presented here on steps/day and metabolic syndrome, and elsewhere on physical activity and other health and disease states, suggest that it is a fundamental component of daily living.
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