These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [A case of giant advanced ulcerative breast cancer managed with epirubicin and cyclophosphamide followed by weekly paclitaxel].
    Author: Moriya T, Fukatsu K, Ueda S, Iwaya K, Osaki A, Yamamoto J.
    Journal: Gan To Kagaku Ryoho; 2010 May; 37(5):907-10. PubMed ID: 20495326.
    Abstract:
    We report a case of giant advanced breast cancer with skin ulceration and bleeding (T4cN3M0, Stage IIIC) in which a significant QOL improvement was achieved with epirubicin and cyclophosphamide (EC) followed by weekly paclitaxel. A 63- year-old postmenopausal woman presented in May 2008 with a giant ulcerated right breast tumor and extensive erythema of the involved skin. She had discovered the tumor the previous year, but had not sought medical advice or treatment. A core needle biopsy of the breast mass led to a diagnosis of an invasive ductal carcinoma negative for estrogen receptor, progester-one receptor, and HER2/neu protein expression. She received q3w 4 cycles of EC(E: 60 mg/m(2), C: 600 mg/m(2))and 12 cycles of weekly paclitaxel (80 mg/m(2)). Upon completion of this chemotherapy, the breast tumor and skin erythema had nearly disappeared. A mastectomy was then performed with partial resection of the muscle and axillary lymph node dissection. Pathological examination showed only focal residual tumor cells and complete disappearance of cancer cells in the lymph nodes (Grade 2). EC followed by weekly paclitaxel therapy was effective for the locally advanced ulcerative breast tumor, and significantly improved QOL in this patient with Stage III C advanced breast cancer.
    [Abstract] [Full Text] [Related] [New Search]