These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Dimethylsulfoxide-induced expression of thymic stromal lymphopoietin in human bronchial epithelial cells].
    Author: Zhang D, Cai SX, Zhao HJ, Liu LY.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2010 May; 30(5):963-5. PubMed ID: 20501368.
    Abstract:
    OBJECTIVE: To investigate the effect of dimethylsulfoxide on the expression of thymic stromal lymphopoietin (TSLP) in human bronchial epithelial cell (HBE). METHODS: 16HBE cells were incubated in the presence of dimethylsulfoxide at different concentrations, and the cell proliferation changes were observed. The expressions of TSLP mRNA and protein in the cells were detected by real-time quantitative PCR and ELISA, respectively. RESULTS: Dimethylsulfoxide induced significantly increased TSLP mRNA expression in HBE cells (P<0.01) in a concentration-dependent manner. The level of TSLP protein in the supernatant was also increased after dimethylsulfoxide treatment, but high concentration of dimethylsulfoxide resulted in e inhibited cell proliferation. CONCLUSION: Dimethylsulfoxide may affect the immunomodulatory function of HBE cells.
    [Abstract] [Full Text] [Related] [New Search]