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  • Title: Drug-induced acute kidney injury in the critically ill adult: recognition and prevention strategies.
    Author: Bentley ML, Corwin HL, Dasta J.
    Journal: Crit Care Med; 2010 Jun; 38(6 Suppl):S169-74. PubMed ID: 20502171.
    Abstract:
    Acute kidney injury is common in critically ill patients, with an incidence of 20% to 30%. It has been associated with increased mortality, hospital length of stay, and total cost. A number of strategies may be beneficial in identifying at-risk patients. In addition, using preventive measures and avoiding nephrotoxic medications are paramount in reducing the overall incidence. Although multifactorial, drug-induced acute kidney injury may account for up to 25% of all cases of acute kidney injury in this population. This review focuses on the mechanisms of drug-induced acute kidney injury in critically ill adults and offers preventive strategies when appropriate.
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