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Title: Expression of barley BAX Inhibitor-1 in carrots confers resistance to Botrytis cinerea. Author: Imani J, Baltruschat H, Stein E, Jia G, Vogelsberg J, Kogel KH, Hückelhoven R. Journal: Mol Plant Pathol; 2006 Jul; 7(4):279-84. PubMed ID: 20507447. Abstract: SUMMARY BAX Inhibitor-1 (BI-1) is a protein that controls heterologous BAX-induced cell death, the hypersensitive reaction and abiotic stress-induced cell death in plants. When over-expressed in epidermal cells of barley, barley BI-1 induces susceptibility to the biotrophic fungal pathogen Blumeria graminis. When we expressed barley BI-1 in carrot susceptible to the necrotrophic fungus Botrytis cinerea, we obtained BI-1-mediated resistance to fungus-induced leaf cell death and less fungal spreading on the leaves. Barley BI-1 also mediated resistance to Chalara elegans in carrot roots. The results support the idea that cell death inhibition is an applicable approach to control cell-death-inducing pathogens in crop plants.[Abstract] [Full Text] [Related] [New Search]