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  • Title: Factors affecting β-ODAP content in Lathyrus sativus and their possible physiological mechanisms.
    Author: Jiao CJ, Jiang JL, Ke LM, Cheng W, Li FM, Li ZX, Wang CY.
    Journal: Food Chem Toxicol; 2011 Mar; 49(3):543-9. PubMed ID: 20510335.
    Abstract:
    A neuroexcitatory non-protein amino acid, β-N-oxalyl-L-α,β-diaminopropionic acid (β-ODAP), present in the seeds of the hardy legume crop grass pea (Lathyrus sativus L.), was considered responsible for human lathyrism. The levels of β-ODAP were reported to vary in different tissues during plant development, and to be affected by a wide range of environmental stresses. In this paper, dynamic changes in β-ODAP level at specific stages of plant development as well as the influences of various environmental factors, including nutrient deficiency, drought, salinity, toxic heavy metals, and Rhizobium symbiosis on β-ODAP levels were analyzed, highlighting the relationship between changes in β-ODAP concentrations and Rhizobium growth. Possible mechanisms underlying β-ODAP accumulation are proposed and future research is suggested.
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