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  • Title: Sulfur-adlayer-coated gold electrode for the in vitro electrochemical detection of uric acid in urine.
    Author: Miah MR, Alam MT, Ohsaka T.
    Journal: Anal Chim Acta; 2010 Jun 11; 669(1-2):75-80. PubMed ID: 20510906.
    Abstract:
    The present article demonstrates the electrochemical oxidation of uric acid (UA) at sulfur-adlayer-coated gold (S-Au) electrode in alkaline media. At S-Au electrode, UA oxidized at a significantly lower overpotential with a higher current density as compared to the bare Au electrode. The oxidation of UA at the S-Au electrode is highly selective in the presence of the other commonly existing bio-molecules in urine. The proposed electrochemical sensor not only exhibited good reproducibility, but also showed a fast amperometric response to UA in the concentration range of 0.0025-5 mM with a low detection limit of 0.4 microM.
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