These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Clinical significance of a new technique of microscopic visualization in extrapulmonary tuberculosis].
    Author: Casal M, Clemente MJ.
    Journal: Med Clin (Barc); 1991 Apr 06; 96(13):491-2. PubMed ID: 2051791.
    Abstract:
    BACKGROUND: The aim of this work was the clinical investigation of a new method of microscopy to improve the sensitivity in the diagnosis of tuberculosis in comparison with the actual conventional technique, without detriment of specificity. METHODS: A comparative study between Smithwick fluorescence technique and a new technique named big drop fluorescence has been made with a total of 185 clinical samples of extrapulmonary tuberculosis. All samples were carried in parallel with both technique, the Smithwick usually utilized in the majority of laboratories, and a new technique described recently by us, named big drop fluorescence, that use a sample with more concentration and different times of stain, with the same reagents. RESULTS: A sensitivity of 12.5% and 56.2% respectively was obtained with Smithwick and big drop fluorescence techniques. A specificity of 97.0% with big drop fluorescence and 98.2% with Smithwick was obtained. This improvement of sensibility was very important and the lost of specificity was so little that a statistic difference without both techniques was not observed. CONCLUSIONS: The new technique named big drop fluorescence (BDF) shows greater sensitivity in the microscopical diagnosis of extrapulmonary tuberculosis.
    [Abstract] [Full Text] [Related] [New Search]