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  • Title: [Acute intracranial hypertension during xenon anesthesia in a patient with a giant brainstem tumor and cerebrospinal fluid flow obstruction: a case report].
    Author: Rylova AV, Lubnin AIu, Kutin MA, Beliaev AIu.
    Journal: Anesteziol Reanimatol; 2010; (2):36-9. PubMed ID: 20524329.
    Abstract:
    Today there are prospects for the wide use of xenon for anesthesia or analgesic sedation in neurosurgical patients, but clinical trials of and experience in using the agent in neurosurgery are scanty. The paper reports the first case of acute intracranial hypertension during xenon anesthesia in a patient with a giant brain base tumor and cerebrospinal fluid flow obstruction in the presence of subcompensated intracranial hypertension. Comparison of intracranial pressure, blood pressure, cerebral perfusion pressure, and linear blood flow velocity suggests the nature of the effect of xenon on cerebral vascular tone, cerebral blood flow, and its autoregulation. Based on the findings, the authors discuss whether xenon may be used in patients with intracranial hypertension.
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