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  • Title: [Bone marrow transplantation in the treatment of severe aplastic anemia].
    Author: Locatelli F, Zecca M, Nespoli L, Severi F.
    Journal: Pediatr Med Chir; 1991; 13(1):31-4. PubMed ID: 2052453.
    Abstract:
    Bone marrow transplantation (BMT) in patient affected by severe aplastic anemia (SAA), is successful in 70-80% of cases, when performed with HLA identical brother or syngeneic twin as donors, and in 11-45% of cases when performed from aploidentical-identical related or HLA identical unrelated donor. The different conditioning regimens (Cy alone or in combination with TBI) have shown similar results in the long term outcomes. Cyclosporin-A is very effective in avoiding rejection and controlling GVHD.
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