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  • Title: Domino allylic amination/Sonogashira/heterocyclisation reactions: palladium-catalysed three-component synthesis of pyrroles.
    Author: Lamandé-Langle S, Abarbri M, Thibonnet J, Duchêne A, Parrain JL.
    Journal: Chem Commun (Camb); 2010 Jul 28; 46(28):5157-9. PubMed ID: 20532274.
    Abstract:
    Three-component reactions with 3,4-diiodoalk-2-enoic derivatives, primary amines, and terminal alkynes proceeded to give trisubstituted pyrroles in fair to good yields in the presence of palladium and copper catalysts under mild reaction conditions.
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