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  • Title: Prevalence of non-T-cells in the replication of the N-tropic, type C virus of young AKR mice.
    Author: Gisselbrecht S, Blaineau C, Hurot MA, Pozo F, Levy JP.
    Journal: Cancer Res; 1978 Apr; 38(4):939-41. PubMed ID: 205350.
    Abstract:
    The XC infectious center assay was used to study the nature of the lymphoid cells producing N-tropic C-type viruses in preleukemic AKR mice. Viral production by thymic cell suspensions was very low and was possibly due to contaminating cells. Production at least 100-fold higher was found in spleen cells and was probably due to non-T-cells. The significance of these results is discussed briefly, including the possibility that the N-tropic XC syncitia-inducing type C virus of young AKR mice is not the leukemogenic agent.
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