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  • Title: Synthesis and biological evaluation of new cytotoxic azanaphthoquinone pyrrolo-annelated derivatives.
    Author: Shanab K, Schirmer E, Knafl H, Wulz E, Holzer W, Spreitzer H, Schmidt P, Aicher B, Müller G, Günther E.
    Journal: Bioorg Med Chem Lett; 2010 Jul 01; 20(13):3950-2. PubMed ID: 20537894.
    Abstract:
    A series of azanaphthoquinone pyrrolo-annelated derivatives attached to basic side chains have been synthesized. The antiproliferative activities of all compounds were evaluated on at least four different cell lines. The effects on cell cycle and intercalation were investigated.
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