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  • Title: [Significance of hyponatremia in patients with oropharyngeal tumors].
    Author: Ketteler M, Gross P, Menstell S, Weidauer H.
    Journal: Laryngorhinootologie; 1991 Apr; 70(4):218-20. PubMed ID: 2054029.
    Abstract:
    We observed 29 patients with hyponatremia associated with oropharyngeal carcinoma. In 19/29 the hyponatremia was attributable to a decreased effective arterial blood volume whereas in the remainder (10/29) the presence of SIADH could be demonstrated. These etiologies of hyponatremia were best differentiated by the plasma urea concentration (less than 30 mg/dl in SIADH), urate concentration (less than 4,0 mg/dl in SIADH) and creatinine concentration (less than 0,9 mg/dl in SIADH). Furthermore, SIADH patients had a spontaneous natriuresis. The mainstay of therapy in either form of hyponatremia is fluid restriction (less than 1 l/d).
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