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  • Title: [Group- and type-specific antibodies to the gag-gene protein p26 of the human immunodeficiency virus immunological type 2 in infected patients].
    Author: Kliushnik SIu, Selimova LM, Veselovskaia TV, Zaĭdes VM.
    Journal: Biull Eksp Biol Med; 1991 Mar; 111(3):283-4. PubMed ID: 2054505.
    Abstract:
    The immunoreactivity of serum samples from HIV-2 infected persons was studied by radioimmunoprecipitation assay (RIPA) in homo- and heterotypic variants. In homotypic RIPA all sera studied have precipitated the viral glycoprotein with the high molecular weight, gp170. Some samples were active for gag-gene products, p57 and p26 in homotypic RIPA. Most these samples were also active for heterotypic gag-protein of HIV-1 serotype, p55 and p24. On the other hand anti-gag reactivity of one sample was limited only by homotypic activity. Some causes of this phenomena as well as its significance for serodiagnosis of HIV infection are discussed.
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